Malignant Peripheral Nerve Sheath Tumors
Overview: Malignant peripheral nerve sheath tumors (MPNSTs) are rare cancers that develop from the cells surrounding peripheral nerves. They are aggressive and can invade nearby tissues and organs. MPNSTs can occur anywhere in the body but are most common in the torso and legs.
Symptoms
Symptoms of MPNSTs may include pain, swelling, and changes in the appearance of the affected area. As the tumor grows, it can cause nerve damage and other neurological symptoms, such as weakness or numbness.
Causes
The exact cause of MPNSTs is not known. However, people with a genetic condition called neurofibromatosis type 1 (NF1) have an increased risk of developing these tumors. Other factors that may increase the risk include exposure to radiation and having a history of benign nerve sheath tumors.
FAQ’s
What are the treatment options for MPNSTs?
The main treatment for MPNSTs is surgery to remove the tumor. In some cases, radiation therapy or chemotherapy may also be used.
Can MPNSTs be prevented?
There is currently no way to prevent MPNSTs. However, early detection and prompt treatment can increase the chances of a successful outcome.
Are MPNSTs hereditary?
In some cases, MPNSTs can be hereditary, particularly in people with NF1. However, most cases are not inherited and occur spontaneously.
Is it possible to have more than one MPNST?
Yes, it is possible to have multiple MPNSTs in different parts of the body.
How long does someone with MPNST usually live?
The prognosis for people with MPNSTs varies depending on the size and location of the tumor, as well as other factors such as the person’s overall health. In some cases, MPNSTs can be effectively treated and do not recur, while in others, the tumors may grow back or spread to other parts of the body.
